| England-Premier League - Saison 2021/22 - Spielplan | ||||||
| Datum | Heimmannschaft | : | Gastmannschaft | Tore | ||
| 1. Spieltag | ||||||
| 13.08.2021, 21:00 | Brentford FC | : | Arsenal FC | 2 | : | 0 |
| 14.08.2021, 13:30 | Manchester United | : | Leeds United | 5 | : | 1 |
| 14.08.2021, 16:00 | Burnley FC | : | Brighton & Hove Albion | 1 | : | 2 |
| 14.08.2021, 16:00 | Chelsea FC | : | Crystal Palace | 3 | : | 0 |
| 14.08.2021, 16:00 | Everton FC | : | Southampton FC | 3 | : | 1 |
| 14.08.2021, 16:00 | Leicester City | : | Wolverhampton Wanderers | 1 | : | 0 |
| 14.08.2021, 16:00 | Watford FC | : | Aston Villa | 3 | : | 2 |
| 14.08.2021, 18:30 | Norwich City | : | Liverpool FC | 0 | : | 3 |
| 15.08.2021, 15:00 | Newcastle United | : | West Ham United | 2 | : | 4 |
| 15.08.2021, 17:30 | Tottenham Hotspur | : | Manchester City | 1 | : | 0 |
| 2. Spieltag | ||||||
| 21.08.2021, 13:30 | Liverpool FC | : | Burnley FC | 2 | : | 0 |
| 21.08.2021, 16:00 | Aston Villa | : | Newcastle United | 2 | : | 0 |
| 21.08.2021, 16:00 | Crystal Palace | : | Brentford FC | 0 | : | 0 |
| 21.08.2021, 16:00 | Leeds United | : | Everton FC | 2 | : | 2 |
| 21.08.2021, 16:00 | Manchester City | : | Norwich City | 5 | : | 0 |
| 21.08.2021, 18:30 | Brighton & Hove Albion | : | Watford FC | 2 | : | 0 |
| 22.08.2021, 15:00 | Southampton FC | : | Manchester United | 1 | : | 1 |
| 22.08.2021, 15:00 | Wolverhampton Wanderers | : | Tottenham Hotspur | 0 | : | 1 |
| 22.08.2021, 17:30 | Arsenal FC | : | Chelsea FC | 0 | : | 2 |
| 23.08.2021, 21:00 | West Ham United | : | Leicester City | 4 | : | 1 |
| 3. Spieltag | ||||||
| 28.08.2021, 13:30 | Manchester City | : | Arsenal FC | 5 | : | 0 |
| 28.08.2021, 16:00 | Aston Villa | : | Brentford FC | 1 | : | 1 |
| 28.08.2021, 16:00 | Brighton & Hove Albion | : | Everton FC | 0 | : | 2 |
| 28.08.2021, 16:00 | Newcastle United | : | Southampton FC | 2 | : | 2 |
| 28.08.2021, 16:00 | Norwich City | : | Leicester City | 1 | : | 2 |
| 28.08.2021, 16:00 | West Ham United | : | Crystal Palace | 2 | : | 2 |
| 28.08.2021, 18:30 | Liverpool FC | : | Chelsea FC | 1 | : | 1 |
| 29.08.2021, 15:00 | Burnley FC | : | Leeds United | 1 | : | 1 |
| 29.08.2021, 15:00 | Tottenham Hotspur | : | Watford FC | 1 | : | 0 |
| 29.08.2021, 17:30 | Wolverhampton Wanderers | : | Manchester United | 0 | : | 1 |
| 4. Spieltag | ||||||
| 11.09.2021, 13:30 | Crystal Palace | : | Tottenham Hotspur | 3 | : | 0 |
| 11.09.2021, 16:00 | Arsenal FC | : | Norwich City | 1 | : | 0 |
| 11.09.2021, 16:00 | Brentford FC | : | Brighton & Hove Albion | 0 | : | 1 |
| 11.09.2021, 16:00 | Leicester City | : | Manchester City | 0 | : | 1 |
| 11.09.2021, 16:00 | Manchester United | : | Newcastle United | 4 | : | 1 |
| 11.09.2021, 16:00 | Southampton FC | : | West Ham United | 0 | : | 0 |
| 11.09.2021, 16:00 | Watford FC | : | Wolverhampton Wanderers | 0 | : | 2 |
| 11.09.2021, 18:30 | Chelsea FC | : | Aston Villa | 3 | : | 0 |
| 12.09.2021, 17:30 | Leeds United | : | Liverpool FC | 0 | : | 3 |
| 13.09.2021, 21:00 | Everton FC | : | Burnley FC | 3 | : | 1 |
| 5. Spieltag | ||||||
| 17.09.2021, 21:00 | Newcastle United | : | Leeds United | 1 | : | 1 |
| 18.09.2021, 13:30 | Wolverhampton Wanderers | : | Brentford FC | 0 | : | 2 |
| 18.09.2021, 16:00 | Burnley FC | : | Arsenal FC | 0 | : | 1 |
| 18.09.2021, 16:00 | Liverpool FC | : | Crystal Palace | 3 | : | 0 |
| 18.09.2021, 16:00 | Manchester City | : | Southampton FC | 0 | : | 0 |
| 18.09.2021, 16:00 | Norwich City | : | Watford FC | 1 | : | 3 |
| 18.09.2021, 18:30 | Aston Villa | : | Everton FC | 3 | : | 0 |
| 19.09.2021, 15:00 | Brighton & Hove Albion | : | Leicester City | 2 | : | 1 |
| 19.09.2021, 15:00 | West Ham United | : | Manchester United | 1 | : | 2 |
| 19.09.2021, 17:30 | Tottenham Hotspur | : | Chelsea FC | 0 | : | 3 |
| 6. Spieltag | ||||||
| 25.09.2021, 13:30 | Chelsea FC | : | Manchester City | 0 | : | 1 |
| 25.09.2021, 13:30 | Manchester United | : | Aston Villa | 0 | : | 1 |
| 25.09.2021, 16:00 | Everton FC | : | Norwich City | 2 | : | 0 |
| 25.09.2021, 16:00 | Leeds United | : | West Ham United | 1 | : | 2 |
| 25.09.2021, 16:00 | Leicester City | : | Burnley FC | 2 | : | 2 |
| 25.09.2021, 16:00 | Watford FC | : | Newcastle United | 1 | : | 1 |
| 25.09.2021, 18:30 | Brentford FC | : | Liverpool FC | 3 | : | 3 |
| 26.09.2021, 15:00 | Southampton FC | : | Wolverhampton Wanderers | 0 | : | 1 |
| 26.09.2021, 17:30 | Arsenal FC | : | Tottenham Hotspur | 3 | : | 1 |
| 27.09.2021, 21:00 | Crystal Palace | : | Brighton & Hove Albion | 1 | : | 1 |
| 7. Spieltag | ||||||
| 02.10.2021, 13:30 | Manchester United | : | Everton FC | 1 | : | 1 |
| 02.10.2021, 16:00 | Burnley FC | : | Norwich City | 0 | : | 0 |
| 02.10.2021, 16:00 | Chelsea FC | : | Southampton FC | 3 | : | 1 |
| 02.10.2021, 16:00 | Leeds United | : | Watford FC | 1 | : | 0 |
| 02.10.2021, 16:00 | Wolverhampton Wanderers | : | Newcastle United | 2 | : | 1 |
| 02.10.2021, 18:30 | Brighton & Hove Albion | : | Arsenal FC | 0 | : | 0 |
| 03.10.2021, 15:00 | Crystal Palace | : | Leicester City | 2 | : | 2 |
| 03.10.2021, 15:00 | Tottenham Hotspur | : | Aston Villa | 2 | : | 1 |
| 03.10.2021, 15:00 | West Ham United | : | Brentford FC | 1 | : | 2 |
| 03.10.2021, 17:30 | Liverpool FC | : | Manchester City | 2 | : | 2 |
| 8. Spieltag | ||||||
| 16.10.2021, 13:30 | Watford FC | : | Liverpool FC | 0 | : | 5 |
| 16.10.2021, 16:00 | Aston Villa | : | Wolverhampton Wanderers | 2 | : | 3 |
| 16.10.2021, 16:00 | Leicester City | : | Manchester United | 4 | : | 2 |
| 16.10.2021, 16:00 | Manchester City | : | Burnley FC | 2 | : | 0 |
| 16.10.2021, 16:00 | Norwich City | : | Brighton & Hove Albion | 0 | : | 0 |
| 16.10.2021, 16:00 | Southampton FC | : | Leeds United | 1 | : | 0 |
| 16.10.2021, 18:30 | Brentford FC | : | Chelsea FC | 0 | : | 1 |
| 17.10.2021, 15:00 | Everton FC | : | West Ham United | 0 | : | 1 |
| 17.10.2021, 17:30 | Newcastle United | : | Tottenham Hotspur | 2 | : | 3 |
| 18.10.2021, 21:00 | Arsenal FC | : | Crystal Palace | 2 | : | 2 |
| 9. Spieltag | ||||||
| 22.10.2021, 21:00 | Arsenal FC | : | Aston Villa | 3 | : | 1 |
| 23.10.2021, 13:30 | Chelsea FC | : | Norwich City | 7 | : | 0 |
| 23.10.2021, 16:00 | Crystal Palace | : | Newcastle United | 1 | : | 1 |
| 23.10.2021, 16:00 | Everton FC | : | Watford FC | 2 | : | 5 |
| 23.10.2021, 16:00 | Leeds United | : | Wolverhampton Wanderers | 1 | : | 1 |
| 23.10.2021, 16:00 | Southampton FC | : | Burnley FC | 2 | : | 2 |
| 23.10.2021, 18:30 | Brighton & Hove Albion | : | Manchester City | 1 | : | 4 |
| 24.10.2021, 15:00 | Brentford FC | : | Leicester City | 1 | : | 2 |
| 24.10.2021, 15:00 | West Ham United | : | Tottenham Hotspur | 1 | : | 0 |
| 24.10.2021, 17:30 | Manchester United | : | Liverpool FC | 0 | : | 5 |
| 10. Spieltag | ||||||
| 30.10.2021, 13:30 | Leicester City | : | Arsenal FC | 0 | : | 2 |
| 30.10.2021, 16:00 | Burnley FC | : | Brentford FC | 3 | : | 1 |
| 30.10.2021, 16:00 | Liverpool FC | : | Brighton & Hove Albion | 2 | : | 2 |
| 30.10.2021, 16:00 | Manchester City | : | Crystal Palace | 0 | : | 2 |
| 30.10.2021, 16:00 | Newcastle United | : | Chelsea FC | 0 | : | 3 |
| 30.10.2021, 16:00 | Watford FC | : | Southampton FC | 0 | : | 1 |
| 30.10.2021, 18:30 | Tottenham Hotspur | : | Manchester United | 0 | : | 3 |
| 31.10.2021, 15:00 | Norwich City | : | Leeds United | 1 | : | 2 |
| 31.10.2021, 17:30 | Aston Villa | : | West Ham United | 1 | : | 4 |
| 01.11.2021, 21:00 | Wolverhampton Wanderers | : | Everton FC | 2 | : | 1 |
| 11. Spieltag | ||||||
| 05.11.2021, 21:00 | Southampton FC | : | Aston Villa | 1 | : | 0 |
| 06.11.2021, 13:30 | Manchester United | : | Manchester City | 0 | : | 2 |
| 06.11.2021, 16:00 | Crystal Palace | : | Wolverhampton Wanderers | 2 | : | 0 |
| 06.11.2021, 16:00 | Brentford FC | : | Norwich City | 1 | : | 2 |
| 06.11.2021, 16:00 | Chelsea FC | : | Burnley FC | 1 | : | 1 |
| 06.11.2021, 18:30 | Brighton & Hove Albion | : | Newcastle United | 1 | : | 1 |
| 07.11.2021, 15:00 | Arsenal FC | : | Watford FC | 1 | : | 0 |
| 07.11.2021, 15:00 | Everton FC | : | Tottenham Hotspur | 0 | : | 0 |
| 07.11.2021, 15:00 | Leeds United | : | Leicester City | 1 | : | 1 |
| 07.11.2021, 17:30 | West Ham United | : | Liverpool FC | 3 | : | 2 |
| 12. Spieltag | ||||||
| 20.11.2021, 13:30 | Leicester City | : | Chelsea FC | 0 | : | 3 |
| 20.11.2021, 16:00 | Aston Villa | : | Brighton & Hove Albion | 2 | : | 0 |
| 20.11.2021, 16:00 | Burnley FC | : | Crystal Palace | 3 | : | 3 |
| 20.11.2021, 16:00 | Newcastle United | : | Brentford FC | 3 | : | 3 |
| 20.11.2021, 16:00 | Norwich City | : | Southampton FC | 2 | : | 1 |
| 20.11.2021, 16:00 | Watford FC | : | Manchester United | 4 | : | 1 |
| 20.11.2021, 16:00 | Wolverhampton Wanderers | : | West Ham United | 1 | : | 0 |
| 20.11.2021, 18:30 | Liverpool FC | : | Arsenal FC | 4 | : | 0 |
| 21.11.2021, 15:00 | Manchester City | : | Everton FC | 3 | : | 0 |
| 21.11.2021, 17:30 | Tottenham Hotspur | : | Leeds United | 2 | : | 1 |
| 13. Spieltag | ||||||
| 27.11.2021, 13:30 | Arsenal FC | : | Newcastle United | 2 | : | 0 |
| 27.11.2021, 16:00 | Crystal Palace | : | Aston Villa | 1 | : | 2 |
| 27.11.2021, 16:00 | Liverpool FC | : | Southampton FC | 4 | : | 0 |
| 27.11.2021, 16:00 | Norwich City | : | Wolverhampton Wanderers | 0 | : | 0 |
| 27.11.2021, 18:30 | Brighton & Hove Albion | : | Leeds United | 0 | : | 0 |
| 28.11.2021, 15:00 | Brentford FC | : | Everton FC | 1 | : | 0 |
| 28.11.2021, 15:00 | Leicester City | : | Watford FC | 4 | : | 2 |
| 28.11.2021, 15:00 | Manchester City | : | West Ham United | 2 | : | 1 |
| 28.11.2021, 17:30 | Chelsea FC | : | Manchester United | 1 | : | 1 |
| 23.02.2022, 20:30 | Burnley FC | : | Tottenham Hotspur | 1 | : | 0 |
| 14. Spieltag | ||||||
| 30.11.2021, 20:30 | Newcastle United | : | Norwich City | 1 | : | 1 |
| 30.11.2021, 21:15 | Leeds United | : | Crystal Palace | 1 | : | 0 |
| 01.12.2021, 20:30 | Watford FC | : | Chelsea FC | 1 | : | 2 |
| 01.12.2021, 20:30 | West Ham United | : | Brighton & Hove Albion | 1 | : | 1 |
| 01.12.2021, 20:30 | Wolverhampton Wanderers | : | Burnley FC | 0 | : | 0 |
| 01.12.2021, 20:30 | Southampton FC | : | Leicester City | 2 | : | 2 |
| 01.12.2021, 21:15 | Aston Villa | : | Manchester City | 1 | : | 2 |
| 01.12.2021, 21:15 | Everton FC | : | Liverpool FC | 1 | : | 4 |
| 02.12.2021, 20:30 | Tottenham Hotspur | : | Brentford FC | 2 | : | 0 |
| 02.12.2021, 21:15 | Manchester United | : | Arsenal FC | 3 | : | 2 |
| 15. Spieltag | ||||||
| 04.12.2021, 13:30 | West Ham United | : | Chelsea FC | 3 | : | 2 |
| 04.12.2021, 16:00 | Southampton FC | : | Brighton & Hove Albion | 1 | : | 1 |
| 04.12.2021, 16:00 | Newcastle United | : | Burnley FC | 1 | : | 0 |
| 04.12.2021, 16:00 | Wolverhampton Wanderers | : | Liverpool FC | 0 | : | 1 |
| 04.12.2021, 18:30 | Watford FC | : | Manchester City | 1 | : | 3 |
| 05.12.2021, 15:00 | Leeds United | : | Brentford FC | 2 | : | 2 |
| 05.12.2021, 15:00 | Manchester United | : | Crystal Palace | 1 | : | 0 |
| 05.12.2021, 15:00 | Tottenham Hotspur | : | Norwich City | 3 | : | 0 |
| 05.12.2021, 17:30 | Aston Villa | : | Leicester City | 2 | : | 1 |
| 06.12.2021, 21:00 | Everton FC | : | Arsenal FC | 2 | : | 1 |
| 16. Spieltag | ||||||
| 10.12.2021, 21:00 | Brentford FC | : | Watford FC | 2 | : | 1 |
| 11.12.2021, 13:30 | Manchester City | : | Wolverhampton Wanderers | 1 | : | 0 |
| 11.12.2021, 16:00 | Arsenal FC | : | Southampton FC | 3 | : | 0 |
| 11.12.2021, 16:00 | Chelsea FC | : | Leeds United | 3 | : | 2 |
| 11.12.2021, 16:00 | Liverpool FC | : | Aston Villa | 1 | : | 0 |
| 11.12.2021, 18:30 | Norwich City | : | Manchester United | 0 | : | 1 |
| 12.12.2021, 15:00 | Burnley FC | : | West Ham United | 0 | : | 0 |
| 12.12.2021, 15:00 | Leicester City | : | Newcastle United | 4 | : | 0 |
| 12.12.2021, 17:30 | Crystal Palace | : | Everton FC | 3 | : | 1 |
| 16.03.2022, 20:30 | Brighton & Hove Albion | : | Tottenham Hotspur | 0 | : | 2 |
| 17. Spieltag | ||||||
| 14.12.2021, 20:45 | Norwich City | : | Aston Villa | 0 | : | 2 |
| 14.12.2021, 21:00 | Manchester City | : | Leeds United | 7 | : | 0 |
| 15.12.2021, 20:30 | Brighton & Hove Albion | : | Wolverhampton Wanderers | 0 | : | 1 |
| 15.12.2021, 20:30 | Crystal Palace | : | Southampton FC | 2 | : | 2 |
| 15.12.2021, 21:00 | Arsenal FC | : | West Ham United | 2 | : | 0 |
| 16.12.2021, 20:45 | Chelsea FC | : | Everton FC | 1 | : | 1 |
| 16.12.2021, 21:00 | Liverpool FC | : | Newcastle United | 3 | : | 1 |
| 19.01.2022, 20:30 | Leicester City | : | Tottenham Hotspur | 2 | : | 3 |
| 19.01.2022, 21:00 | Brentford FC | : | Manchester United | 1 | : | 3 |
| 05.02.2022, 19:00 | Burnley FC | : | Watford FC | 0 | : | 0 |
| 18. Spieltag | ||||||
| 18.12.2021, 18:30 | Leeds United | : | Arsenal FC | 1 | : | 4 |
| 19.12.2021, 15:00 | Newcastle United | : | Manchester City | 0 | : | 4 |
| 19.12.2021, 15:00 | Wolverhampton Wanderers | : | Chelsea FC | 0 | : | 0 |
| 19.12.2021, 17:30 | Tottenham Hotspur | : | Liverpool FC | 2 | : | 2 |
| 11.01.2022, 20:45 | Southampton FC | : | Brentford FC | 4 | : | 1 |
| 12.01.2022, 20:45 | West Ham United | : | Norwich City | 2 | : | 0 |
| 15.02.2022, 21:15 | Manchester United | : | Brighton & Hove Albion | 2 | : | 0 |
| 23.02.2022, 20:30 | Watford FC | : | Crystal Palace | 1 | : | 4 |
| 20.04.2022, 20:45 | Everton FC | : | Leicester City | 1 | : | 1 |
| 19.05.2022, 21:00 | Aston Villa | : | Burnley FC | 1 | : | 1 |
| 19. Spieltag | ||||||
| 26.12.2021, 16:00 | Manchester City | : | Leicester City | 6 | : | 3 |
| 26.12.2021, 16:00 | Norwich City | : | Arsenal FC | 0 | : | 5 |
| 26.12.2021, 16:00 | Tottenham Hotspur | : | Crystal Palace | 3 | : | 0 |
| 26.12.2021, 16:00 | West Ham United | : | Southampton FC | 2 | : | 3 |
| 26.12.2021, 18:30 | Aston Villa | : | Chelsea FC | 1 | : | 3 |
| 26.12.2021, 21:00 | Brighton & Hove Albion | : | Brentford FC | 2 | : | 0 |
| 27.12.2021, 21:00 | Newcastle United | : | Manchester United | 1 | : | 1 |
| 23.02.2022, 20:45 | Liverpool FC | : | Leeds United | 6 | : | 0 |
| 10.03.2022, 20:30 | Wolverhampton Wanderers | : | Watford FC | 4 | : | 0 |
| 06.04.2022, 20:30 | Burnley FC | : | Everton FC | 3 | : | 2 |
| 20. Spieltag | ||||||
| 28.12.2021, 16:00 | Crystal Palace | : | Norwich City | 3 | : | 0 |
| 28.12.2021, 16:00 | Southampton FC | : | Tottenham Hotspur | 1 | : | 1 |
| 28.12.2021, 16:00 | Watford FC | : | West Ham United | 1 | : | 4 |
| 28.12.2021, 21:00 | Leicester City | : | Liverpool FC | 1 | : | 0 |
| 29.12.2021, 20:30 | Chelsea FC | : | Brighton & Hove Albion | 1 | : | 1 |
| 29.12.2021, 21:15 | Brentford FC | : | Manchester City | 0 | : | 1 |
| 30.12.2021, 21:15 | Manchester United | : | Burnley FC | 3 | : | 1 |
| 24.02.2022, 20:45 | Arsenal FC | : | Wolverhampton Wanderers | 2 | : | 1 |
| 10.03.2022, 20:45 | Leeds United | : | Aston Villa | 0 | : | 3 |
| 17.03.2022, 20:45 | Everton FC | : | Newcastle United | 1 | : | 0 |
| 21. Spieltag | ||||||
| 01.01.2022, 13:30 | Arsenal FC | : | Manchester City | 1 | : | 2 |
| 01.01.2022, 16:00 | Watford FC | : | Tottenham Hotspur | 0 | : | 1 |
| 01.01.2022, 18:30 | Crystal Palace | : | West Ham United | 2 | : | 3 |
| 02.01.2022, 15:00 | Brentford FC | : | Aston Villa | 2 | : | 1 |
| 02.01.2022, 15:00 | Everton FC | : | Brighton & Hove Albion | 2 | : | 3 |
| 02.01.2022, 15:00 | Leeds United | : | Burnley FC | 3 | : | 1 |
| 02.01.2022, 17:30 | Chelsea FC | : | Liverpool FC | 2 | : | 2 |
| 03.01.2022, 18:30 | Manchester United | : | Wolverhampton Wanderers | 0 | : | 1 |
| 10.03.2022, 20:30 | Southampton FC | : | Newcastle United | 1 | : | 2 |
| 11.05.2022, 20:45 | Leicester City | : | Norwich City | 3 | : | 0 |
| 22. Spieltag | ||||||
| 14.01.2022, 21:00 | Brighton & Hove Albion | : | Crystal Palace | 1 | : | 1 |
| 15.01.2022, 13:30 | Manchester City | : | Chelsea FC | 1 | : | 0 |
| 15.01.2022, 16:00 | Norwich City | : | Everton FC | 2 | : | 1 |
| 15.01.2022, 16:00 | Wolverhampton Wanderers | : | Southampton FC | 3 | : | 1 |
| 15.01.2022, 16:00 | Newcastle United | : | Watford FC | 1 | : | 1 |
| 15.01.2022, 18:30 | Aston Villa | : | Manchester United | 2 | : | 2 |
| 16.01.2022, 15:00 | Liverpool FC | : | Brentford FC | 3 | : | 0 |
| 16.01.2022, 15:00 | West Ham United | : | Leeds United | 2 | : | 3 |
| 01.03.2022, 20:45 | Burnley FC | : | Leicester City | 0 | : | 2 |
| 12.05.2022, 20:45 | Tottenham Hotspur | : | Arsenal FC | 3 | : | 0 |
| 23. Spieltag | ||||||
| 21.01.2022, 21:00 | Watford FC | : | Norwich City | 0 | : | 3 |
| 22.01.2022, 13:30 | Everton FC | : | Aston Villa | 0 | : | 1 |
| 22.01.2022, 16:00 | Brentford FC | : | Wolverhampton Wanderers | 1 | : | 2 |
| 22.01.2022, 16:00 | Leeds United | : | Newcastle United | 0 | : | 1 |
| 22.01.2022, 16:00 | Manchester United | : | West Ham United | 1 | : | 0 |
| 22.01.2022, 18:30 | Southampton FC | : | Manchester City | 1 | : | 1 |
| 23.01.2022, 15:00 | Crystal Palace | : | Liverpool FC | 1 | : | 3 |
| 23.01.2022, 15:00 | Arsenal FC | : | Burnley FC | 0 | : | 0 |
| 23.01.2022, 15:00 | Leicester City | : | Brighton & Hove Albion | 1 | : | 1 |
| 23.01.2022, 17:30 | Chelsea FC | : | Tottenham Hotspur | 2 | : | 0 |
| 24. Spieltag | ||||||
| 18.01.2022, 21:00 | Brighton & Hove Albion | : | Chelsea FC | 1 | : | 1 |
| 08.02.2022, 20:45 | Newcastle United | : | Everton FC | 3 | : | 1 |
| 08.02.2022, 20:45 | West Ham United | : | Watford FC | 1 | : | 0 |
| 08.02.2022, 21:00 | Burnley FC | : | Manchester United | 1 | : | 1 |
| 09.02.2022, 20:45 | Manchester City | : | Brentford FC | 2 | : | 0 |
| 09.02.2022, 20:45 | Norwich City | : | Crystal Palace | 1 | : | 1 |
| 09.02.2022, 20:45 | Tottenham Hotspur | : | Southampton FC | 2 | : | 3 |
| 09.02.2022, 21:00 | Aston Villa | : | Leeds United | 3 | : | 3 |
| 10.02.2022, 20:45 | Wolverhampton Wanderers | : | Arsenal FC | 0 | : | 1 |
| 10.02.2022, 20:45 | Liverpool FC | : | Leicester City | 2 | : | 0 |
| 25. Spieltag | ||||||
| 12.02.2022, 13:30 | Manchester United | : | Southampton FC | 1 | : | 1 |
| 12.02.2022, 16:00 | Brentford FC | : | Crystal Palace | 0 | : | 0 |
| 12.02.2022, 16:00 | Everton FC | : | Leeds United | 3 | : | 0 |
| 12.02.2022, 16:00 | Watford FC | : | Brighton & Hove Albion | 0 | : | 2 |
| 12.02.2022, 18:30 | Norwich City | : | Manchester City | 0 | : | 4 |
| 13.02.2022, 15:00 | Burnley FC | : | Liverpool FC | 0 | : | 1 |
| 13.02.2022, 15:00 | Newcastle United | : | Aston Villa | 1 | : | 0 |
| 13.02.2022, 15:00 | Tottenham Hotspur | : | Wolverhampton Wanderers | 0 | : | 2 |
| 13.02.2022, 17:30 | Leicester City | : | West Ham United | 2 | : | 2 |
| 20.04.2022, 20:45 | Chelsea FC | : | Arsenal FC | 2 | : | 4 |
| 26. Spieltag | ||||||
| 19.02.2022, 13:30 | West Ham United | : | Newcastle United | 1 | : | 1 |
| 19.02.2022, 16:00 | Arsenal FC | : | Brentford FC | 2 | : | 1 |
| 19.02.2022, 16:00 | Brighton & Hove Albion | : | Burnley FC | 0 | : | 3 |
| 19.02.2022, 16:00 | Crystal Palace | : | Chelsea FC | 0 | : | 1 |
| 19.02.2022, 16:00 | Southampton FC | : | Everton FC | 2 | : | 0 |
| 19.02.2022, 16:00 | Liverpool FC | : | Norwich City | 3 | : | 1 |
| 19.02.2022, 16:00 | Aston Villa | : | Watford FC | 0 | : | 1 |
| 19.02.2022, 18:30 | Manchester City | : | Tottenham Hotspur | 2 | : | 3 |
| 20.02.2022, 15:00 | Leeds United | : | Manchester United | 2 | : | 4 |
| 20.02.2022, 17:30 | Wolverhampton Wanderers | : | Leicester City | 2 | : | 1 |
| 27. Spieltag | ||||||
| 25.02.2022, 21:00 | Southampton FC | : | Norwich City | 2 | : | 0 |
| 26.02.2022, 13:30 | Leeds United | : | Tottenham Hotspur | 0 | : | 4 |
| 26.02.2022, 16:00 | Crystal Palace | : | Burnley FC | 1 | : | 1 |
| 26.02.2022, 16:00 | Brentford FC | : | Newcastle United | 0 | : | 2 |
| 26.02.2022, 16:00 | Manchester United | : | Watford FC | 0 | : | 0 |
| 26.02.2022, 16:30 | Brighton & Hove Albion | : | Aston Villa | 0 | : | 2 |
| 26.02.2022, 18:30 | Everton FC | : | Manchester City | 0 | : | 1 |
| 27.02.2022, 15:00 | West Ham United | : | Wolverhampton Wanderers | 1 | : | 0 |
| 16.03.2022, 21:15 | Arsenal FC | : | Liverpool FC | 0 | : | 2 |
| 19.05.2022, 21:00 | Chelsea FC | : | Leicester City | 1 | : | 1 |
| 28. Spieltag | ||||||
| 05.03.2022, 13:30 | Leicester City | : | Leeds United | 1 | : | 0 |
| 05.03.2022, 16:00 | Newcastle United | : | Brighton & Hove Albion | 2 | : | 1 |
| 05.03.2022, 16:00 | Wolverhampton Wanderers | : | Crystal Palace | 0 | : | 2 |
| 05.03.2022, 16:00 | Norwich City | : | Brentford FC | 1 | : | 3 |
| 05.03.2022, 16:00 | Burnley FC | : | Chelsea FC | 0 | : | 4 |
| 05.03.2022, 16:00 | Aston Villa | : | Southampton FC | 4 | : | 0 |
| 05.03.2022, 18:30 | Liverpool FC | : | West Ham United | 1 | : | 0 |
| 06.03.2022, 15:00 | Watford FC | : | Arsenal FC | 2 | : | 3 |
| 06.03.2022, 17:30 | Manchester City | : | Manchester United | 4 | : | 1 |
| 07.03.2022, 21:00 | Tottenham Hotspur | : | Everton FC | 5 | : | 0 |
| 29. Spieltag | ||||||
| 12.03.2022, 13:30 | Brighton & Hove Albion | : | Liverpool FC | 0 | : | 2 |
| 12.03.2022, 16:00 | Brentford FC | : | Burnley FC | 2 | : | 0 |
| 12.03.2022, 18:30 | Manchester United | : | Tottenham Hotspur | 3 | : | 2 |
| 13.03.2022, 15:00 | Chelsea FC | : | Newcastle United | 1 | : | 0 |
| 13.03.2022, 15:00 | Everton FC | : | Wolverhampton Wanderers | 0 | : | 1 |
| 13.03.2022, 15:00 | Southampton FC | : | Watford FC | 1 | : | 2 |
| 13.03.2022, 15:00 | Leeds United | : | Norwich City | 2 | : | 1 |
| 13.03.2022, 15:00 | West Ham United | : | Aston Villa | 2 | : | 1 |
| 13.03.2022, 17:30 | Arsenal FC | : | Leicester City | 2 | : | 0 |
| 14.03.2022, 21:00 | Crystal Palace | : | Manchester City | 0 | : | 0 |
| 30. Spieltag | ||||||
| 10.03.2022, 20:30 | Norwich City | : | Chelsea FC | 1 | : | 3 |
| 18.03.2022, 21:00 | Wolverhampton Wanderers | : | Leeds United | 2 | : | 3 |
| 19.03.2022, 13:30 | Aston Villa | : | Arsenal FC | 0 | : | 1 |
| 20.03.2022, 15:00 | Leicester City | : | Brentford FC | 2 | : | 1 |
| 20.03.2022, 17:30 | Tottenham Hotspur | : | West Ham United | 3 | : | 1 |
| 19.04.2022, 21:00 | Liverpool FC | : | Manchester United | 4 | : | 0 |
| 20.04.2022, 20:45 | Newcastle United | : | Crystal Palace | 1 | : | 0 |
| 20.04.2022, 21:00 | Manchester City | : | Brighton & Hove Albion | 3 | : | 0 |
| 21.04.2022, 20:45 | Burnley FC | : | Southampton FC | 2 | : | 0 |
| 11.05.2022, 20:45 | Watford FC | : | Everton FC | 0 | : | 0 |
| 31. Spieltag | ||||||
| 02.04.2022, 13:30 | Liverpool FC | : | Watford FC | 2 | : | 0 |
| 02.04.2022, 16:00 | Brighton & Hove Albion | : | Norwich City | 0 | : | 0 |
| 02.04.2022, 16:00 | Burnley FC | : | Manchester City | 0 | : | 2 |
| 02.04.2022, 16:00 | Chelsea FC | : | Brentford FC | 1 | : | 4 |
| 02.04.2022, 16:00 | Leeds United | : | Southampton FC | 1 | : | 1 |
| 02.04.2022, 16:00 | Wolverhampton Wanderers | : | Aston Villa | 2 | : | 1 |
| 02.04.2022, 18:30 | Manchester United | : | Leicester City | 1 | : | 1 |
| 03.04.2022, 15:00 | West Ham United | : | Everton FC | 2 | : | 1 |
| 03.04.2022, 17:30 | Tottenham Hotspur | : | Newcastle United | 5 | : | 1 |
| 04.04.2022, 21:00 | Crystal Palace | : | Arsenal FC | 3 | : | 0 |
| 32. Spieltag | ||||||
| 08.04.2022, 21:00 | Newcastle United | : | Wolverhampton Wanderers | 1 | : | 0 |
| 09.04.2022, 13:30 | Everton FC | : | Manchester United | 1 | : | 0 |
| 09.04.2022, 16:00 | Arsenal FC | : | Brighton & Hove Albion | 1 | : | 2 |
| 09.04.2022, 16:00 | Southampton FC | : | Chelsea FC | 0 | : | 6 |
| 09.04.2022, 16:00 | Watford FC | : | Leeds United | 0 | : | 3 |
| 09.04.2022, 18:30 | Aston Villa | : | Tottenham Hotspur | 0 | : | 4 |
| 10.04.2022, 15:00 | Norwich City | : | Burnley FC | 2 | : | 0 |
| 10.04.2022, 15:00 | Leicester City | : | Crystal Palace | 2 | : | 1 |
| 10.04.2022, 15:00 | Brentford FC | : | West Ham United | 2 | : | 0 |
| 10.04.2022, 17:30 | Manchester City | : | Liverpool FC | 2 | : | 2 |
| 33. Spieltag | ||||||
| 16.04.2022, 13:30 | Tottenham Hotspur | : | Brighton & Hove Albion | 0 | : | 1 |
| 16.04.2022, 16:00 | Southampton FC | : | Arsenal FC | 1 | : | 0 |
| 16.04.2022, 16:00 | Watford FC | : | Brentford FC | 1 | : | 2 |
| 16.04.2022, 16:00 | Manchester United | : | Norwich City | 3 | : | 2 |
| 17.04.2022, 15:15 | Newcastle United | : | Leicester City | 2 | : | 1 |
| 17.04.2022, 15:15 | West Ham United | : | Burnley FC | 1 | : | 1 |
| 10.05.2022, 21:00 | Aston Villa | : | Liverpool FC | 1 | : | 2 |
| 11.05.2022, 20:30 | Leeds United | : | Chelsea FC | 0 | : | 3 |
| 11.05.2022, 21:15 | Wolverhampton Wanderers | : | Manchester City | 1 | : | 5 |
| 19.05.2022, 20:45 | Everton FC | : | Crystal Palace | 3 | : | 2 |
| 34. Spieltag | ||||||
| 23.04.2022, 13:30 | Arsenal FC | : | Manchester United | 3 | : | 1 |
| 23.04.2022, 16:00 | Leicester City | : | Aston Villa | 0 | : | 0 |
| 23.04.2022, 16:00 | Manchester City | : | Watford FC | 5 | : | 1 |
| 23.04.2022, 16:00 | Norwich City | : | Newcastle United | 0 | : | 3 |
| 23.04.2022, 18:30 | Brentford FC | : | Tottenham Hotspur | 0 | : | 0 |
| 24.04.2022, 15:00 | Brighton & Hove Albion | : | Southampton FC | 2 | : | 2 |
| 24.04.2022, 15:00 | Burnley FC | : | Wolverhampton Wanderers | 1 | : | 0 |
| 24.04.2022, 15:00 | Chelsea FC | : | West Ham United | 1 | : | 0 |
| 24.04.2022, 17:30 | Liverpool FC | : | Everton FC | 2 | : | 0 |
| 25.04.2022, 21:00 | Crystal Palace | : | Leeds United | 0 | : | 0 |
| 35. Spieltag | ||||||
| 30.04.2022, 13:30 | Newcastle United | : | Liverpool FC | 0 | : | 1 |
| 30.04.2022, 16:00 | Aston Villa | : | Norwich City | 2 | : | 0 |
| 30.04.2022, 16:00 | Southampton FC | : | Crystal Palace | 1 | : | 2 |
| 30.04.2022, 16:00 | Watford FC | : | Burnley FC | 1 | : | 2 |
| 30.04.2022, 16:00 | Wolverhampton Wanderers | : | Brighton & Hove Albion | 0 | : | 3 |
| 30.04.2022, 18:30 | Leeds United | : | Manchester City | 0 | : | 4 |
| 01.05.2022, 15:00 | Everton FC | : | Chelsea FC | 1 | : | 0 |
| 01.05.2022, 15:00 | Tottenham Hotspur | : | Leicester City | 3 | : | 1 |
| 01.05.2022, 17:30 | West Ham United | : | Arsenal FC | 1 | : | 2 |
| 02.05.2022, 21:00 | Manchester United | : | Brentford FC | 3 | : | 0 |
| 36. Spieltag | ||||||
| 07.05.2022, 16:00 | Burnley FC | : | Aston Villa | 1 | : | 3 |
| 07.05.2022, 16:00 | Brentford FC | : | Southampton FC | 3 | : | 0 |
| 07.05.2022, 16:00 | Crystal Palace | : | Watford FC | 1 | : | 0 |
| 07.05.2022, 16:00 | Chelsea FC | : | Wolverhampton Wanderers | 2 | : | 2 |
| 07.05.2022, 18:30 | Brighton & Hove Albion | : | Manchester United | 4 | : | 0 |
| 07.05.2022, 20:45 | Liverpool FC | : | Tottenham Hotspur | 1 | : | 1 |
| 08.05.2022, 15:00 | Leicester City | : | Everton FC | 1 | : | 2 |
| 08.05.2022, 15:00 | Arsenal FC | : | Leeds United | 2 | : | 1 |
| 08.05.2022, 15:00 | Norwich City | : | West Ham United | 0 | : | 4 |
| 08.05.2022, 17:30 | Manchester City | : | Newcastle United | 5 | : | 0 |
| 37. Spieltag | ||||||
| 28.04.2022, 20:45 | Manchester United | : | Chelsea FC | 1 | : | 1 |
| 15.05.2022, 13:00 | Tottenham Hotspur | : | Burnley FC | 1 | : | 0 |
| 15.05.2022, 15:00 | Aston Villa | : | Crystal Palace | 1 | : | 1 |
| 15.05.2022, 15:00 | Watford FC | : | Leicester City | 1 | : | 5 |
| 15.05.2022, 15:00 | Leeds United | : | Brighton & Hove Albion | 1 | : | 1 |
| 15.05.2022, 15:00 | West Ham United | : | Manchester City | 2 | : | 2 |
| 15.05.2022, 15:00 | Wolverhampton Wanderers | : | Norwich City | 1 | : | 1 |
| 15.05.2022, 17:30 | Everton FC | : | Brentford FC | 2 | : | 3 |
| 16.05.2022, 21:00 | Newcastle United | : | Arsenal FC | 2 | : | 0 |
| 17.05.2022, 20:45 | Southampton FC | : | Liverpool FC | 1 | : | 2 |
| 38. Spieltag | ||||||
| 22.05.2022, 17:00 | Arsenal FC | : | Everton FC | 5 | : | 1 |
| 22.05.2022, 17:00 | Brentford FC | : | Leeds United | 1 | : | 2 |
| 22.05.2022, 17:00 | Brighton & Hove Albion | : | West Ham United | 3 | : | 1 |
| 22.05.2022, 17:00 | Burnley FC | : | Newcastle United | 1 | : | 2 |
| 22.05.2022, 17:00 | Chelsea FC | : | Watford FC | 2 | : | 1 |
| 22.05.2022, 17:00 | Crystal Palace | : | Manchester United | 1 | : | 0 |
| 22.05.2022, 17:00 | Leicester City | : | Southampton FC | 4 | : | 1 |
| 22.05.2022, 17:00 | Liverpool FC | : | Wolverhampton Wanderers | 3 | : | 1 |
| 22.05.2022, 17:00 | Manchester City | : | Aston Villa | 3 | : | 2 |
| 22.05.2022, 17:00 | Norwich City | : | Tottenham Hotspur | 0 | : | 5 |